Platforms and software systems for an autonomic internet

The current Internet does not enable easy introduction and deployment of new network technologies and services. This paper aims to progress the Future Internet (FI) by introduction of a service composition and execution environment that re-use existing components of access and core networks. This paper presents essential service-centric platforms and software systems that have been developed with the aim to create a flexible environment for an Autonomic Internet.Peer ReviewedPostprint (published version

Manageability of future internet virtual networks from a practical viewpoint

The Autonomic Internet project [1] approach relies on abstractions and distributed systems of a five plane solution for the provision of Future Internet Services (OSKMV): Orchestration, Service Enablers, Knowledge, Management and Virtualisation Planes. This paper presents a practical viewpoint of the manageability of virtual networks, exercising the components and systems that integrate this approach and that are being validated. This paper positions the distributed systems and networking services that integrate this solution, focusing on the provision of Future Internet services for self-configuration and selfperformance management scene

Manageability of future internet virtual networks from a practical viewpoint

The Autonomic Internet project [1] approach relies on abstractions and distributed systems of a five plane solution for the provision of Future Internet Services (OSKMV): Orchestration, Service Enablers, Knowledge, Management and Virtualisation Planes. This paper presents a practical viewpoint of the manageability of virtual networks, exercising the components and systems that integrate this approach and that are being validated. This paper positions the distributed systems and networking services that integrate this solution, focusing on the provision of Future Internet services for self-configuration and selfperformance management scenesPostprint (published version

Platforms and software systems for an autonomic internet

The current Internet does not enable easy introduction and deployment of new network technologies and services. This paper aims to progress the Future Internet (FI) by introduction of a service composition and execution environment that re-use existing components of access and core networks. This paper presents essential service-centric platforms and software systems that have been developed with the aim to create a flexible environment for an Autonomic Internet.Peer Reviewe

Manageability of future internet virtual networks from a practical viewpoint

The Autonomic Internet project [1] approach relies on abstractions and distributed systems of a five plane solution for the provision of Future Internet Services (OSKMV): Orchestration, Service Enablers, Knowledge, Management and Virtualisation Planes. This paper presents a practical viewpoint of the manageability of virtual networks, exercising the components and systems that integrate this approach and that are being validated. This paper positions the distributed systems and networking services that integrate this solution, focusing on the provision of Future Internet services for self-configuration and selfperformance management scene

The advantage of channeling nucleotides for very processive functions

Nucleoside triphosphate (NTP)s, like ATP (adenosine 5’-triphosphate) and GTP (guanosine 5’-triphosphate), have long been considered sufficiently concentrated and diffusible to fuel all cellular ATPases (adenosine triphosphatases) and GTPases (guanosine triphosphatases) in an energetically healthy cell without becoming limiting for function. However, increasing evidence for the importance of local ATP and GTP pools, synthesised in close proximity to ATP- or GTP-consuming reactions, has fundamentally challenged our view of energy metabolism. It has become evident that cellular energy metabolism occurs in many specialised ‘microcompartments’, where energy in the form of NTPs is transferred preferentially from NTP-generating modules directly to NTP-consuming modules. Such energy channeling occurs when diffusion through the cytosol is limited, where these modules are physically close and, in particular, if the NTP-consuming reaction has a very high turnover, i.e. is very processive. Here, we summarise the evidence for these conclusions and describe new insights into the physiological importance and molecular mechanisms of energy channeling gained from recent studies. In particular, we describe the role of glycolytic enzymes for axonal vesicle transport and nucleoside diphosphate kinases for the functions of dynamins and dynamin-related GTPases